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2021-02-27: SiDock@home, SiDock@home becomes a general drug discovery project

Hello everyone!

We are happy to announce that SiDock@home will continue as a general drug discovery project, not limited to coronavirus only! This means that the project will continue for a long time. We aim to develop and incorporate novel methods of drug design and perform drug discovery for different diseases.

Nevertheless, the first mission on fighting the coronavirus continues! There are many results to process and more targets to explore within what started from COVID.SI project.

With best wishes,
Natalia and the team.

2021-02-26: Asteroids@home, Server status update

BOINC server is now running but it is still a temporary solution and there is still some additional work that needs to be done. New workunits should be available in a week or two.

Radim Van?o (FoxKyong)

2021-02-26: WEP-M+2 Project, P2203:170000000 wu's (of 10000 trials each equiv.) processed!

Thanks to all the users. (Please keep crunching!)

2021-02-24: MLC@Home, [TWIM Notes] Feb 23 2021 posted

MLC@Home has posted the Feb 23 2021 edition of its weekly "This Week In MLC@Home" newsletter!
Paper updates, a note about the larger datasets, and more...

Read the update and join the discussion here.

2021-02-24: MLC@Home, [TWIM Notes] Feb 23 2021

This Week in MLC@Home
Notes for Feb 23 2021
A weekly summary of news and notes for MLC@Home

Summary
A small update this week since there's not much news overall. Honestly, yours truly got a little swamped with other things in life and needed to take care of some other things last week. Buy we're back this week, and other than an unexpectedly empty CPU queue for about half a day last week (since corrected), the project has continued and you volunteers have carved off another large chunk of datasets 1, 2 and 3.

The paper is coming along nicely, and we're finally happy with the data and analysis we want at this point, so it's just writing. Some tables and graphs have been posted to Twitter if you'd like to follow along. Honestly, we're about 3 months overdue to get this out to at least arXiv, but we hope it'll be worth the wait. Most of that time was spent tweaking algorithms to get better results, and the datasets/feature vectors are too large fit on an 8GB GPU, so it's mostly CPU training. 18 hours for an epoch is not uncommon. On the bright side, what we're learning doing this will help DS4 when it's available.

DS3-500 and DS3-1000 are complete and ready to upload, but we're still deciding the best place to host such large files. Seeding a torrent off the main server would cut into the already limited bandwidth. We'll need a better solution, for now they exist on a backed-up data drive, and available by individual request.

Other News
DS4 remains on hold until after the paper is finished. We're discussing internally allowing Gridcoin to whitelist this project. If the MLC community has strong opinions either way, please post them below. There are still one or two things that we want to change before that either way, but the list of technical barriers on our side is almost empty. Reminder: the MLC client is open source, and has an issues list at gitlab. If you're a programmer of data scientist and want to help, feel free to look over the issues and submit a pull request.


Project status snapshot:
(note these numbers are approximations)






Last week's TWIM Notes: Feb 8 2021

Thanks again to all our volunteers!

-- The MLC@Home Admins(s)
Homepage: https://www.mlcathome.org/
Twitter: @MLCHome2

2021-02-23: World Community Grid, January/February Update: Smash Childhood Cancer

Lab testing has begun for several drug candidates that may target proteins that play a role in certain childhood cancers.

2021-02-19: WEP-M+2 Project, 12-digit factor of P2203 has now been found by the project...

...282617 times - still no sign of any larger factors

2021-02-18: World Community Grid, January/February Update: Africa Rainfall Project

The researchers continue to promote the project while making plans for data analysis.

2021-02-16: World Community Grid, January/February Update: Mapping Cancer Markers

Work continues on a paper about lung cancer markers.

2021-02-15: BOINC, New BOINC Android client released

Version 7.16.16 of the BOINC Android client has been released. This is the first new Android version in over 4 years, and is a major rewrite of the GUI. Thanks for Vitalii Koshura, Tal Regev, and Isira Seneviratne for their work on this.

The new version is available from the BOINC web site and (for Amazon Fire tablets) from the Amazon app store. It's not on the Google play store because of new restrictions imposed by Google; hopefully this will be resolved in a future version.

2021-02-15: Kryptos@Home, Trello board added

We've added a Trello board for transparently keeping track of current progress, related to reported issues, requested features and ongoing work items. It's also accessible from the web-page menu, via "Project" -> "Trello".

2021-02-15: GPUGRID, New D3RBanditTest workunits

Dears,

as you may have noticed, we sent a new batch of WUs for a new experiment. This time the WUs are rather large and require relatively new cards. For reference, should be ~18h on a 1080 Ti.

Thanks!

T

2021-02-12: World Community Grid, Planned Maintenance on Monday, February 15, 2021 [Completed]

We are updating the software on our servers on Monday, February 15, beginning at 19:00 UTC.

2021-02-12: World Community Grid, Planned Maintenance on Monday, February 15, 2021

We are updating the software on our servers on Monday, February 15, beginning at 19:00 UTC.

2021-02-11: World Community Grid, January/February Update: Microbiome Immunity Project

The scientists are continuing to work on papers related to the research being done on World Community Grid.

2021-02-10: Minecraft@Home, 23 tall blocks cactus found by PDW and edjotron

We've discovered the first naturally generated 23-Tall Cactus! Thanks to PDW and Edjotron, we can now confirm that the tallest is 23 blocks. To see this cacti in its natural habitat, right by a Mesa, please input the seed 184693195438010998 on 1.14 and use /tp 16274576 64 10230656 to teleport to it, right next to the badlands!

As some of you may have seen on the BOINC Forums News updates, developers Balint, Hy and Boincboi have confirmed stability of our new optimization updates. These optimizations to Kaktwoos will allow many models of AMD GPUs to get between 30 and 50% performance, like the RX 480 and RX Vega series. Additionally, some RTX 2000 series graphics cards may see small boost in speed, of 5-10%, while a few (such as an RTX 2060) may see up to 75% more performance!

This means almost all of you can compute cacti much faster, as we launch the next round of Kaktwoos at y=65 shortly.




PDW: https://minecraftathome.com/minecrafthome/view_profile.php?userid=316
edjotron: https://minecraftathome.com/minecrafthome/show_user.php?userid=13486619

2021-02-10: iThena, Dedicated DNS servers available (as part of optimization)

Applications (especially CNode) can now make significant use of DNS servers.

To avoid overloading other servers (not necessarily your ISP) you can use our DNS servers:

ns1.cybercomplex.net
Location: Germany/Frankfurt
IPv4: 51.75.75.243
IPv6: 2001:41d0:701:1100::452

ns2.cybercomplex.net
Location: Canada/Beauharnois
IPv4: 142.4.202.62
IPv6: 2607:5300:101:0:0:0:0:75d

ns3.cybercomplex.net
Location: Poland/Warsaw
IPv4: 80.211.250.127
IPv6: fe80::250:56ff:fea9:8da0

ns4.cybercomplex.net
Location: Australia/Sydney
IPv4: 139.99.170.90
IPv6: 2402:1f00:8100:400::125a

You can also set up your own DNS server (or just DNS cache) on your LAN.
This is especially important if you have several/many BOINC clients and CNode app.
You can check which of the above DNS will be the best (geolocation).

2021-02-09: MLC@Home, [TWIM Notes] Feb 8 2021 posted

MLC@Home has posted the Feb 8 2021 edition of its weekly "This Week In MLC@Home" newsletter!
Its Dataset week! This week MLC@Home releases the first round of datasets computed by our volunteers. They are available for download at the https://www.mlcathome.org/ website. These datasets will help scientists better understand neural networks.

Read the update and join the discussion here.

2021-02-09: MLC@Home, [TWIM Notes] Feb 8 2021

This Week in MLC@Home
Notes for Feb 8 2021
A weekly summary of news and notes for MLC@Home

Summary
It's Dataset week!

We've been working behind the scenes on a paper for analysis of the results you, our volunteers have created so far. The paper is still in progress, but we've waited long enough to release the datasets themselves. Over the next few days, you'll see more and more datasets come available for download at https://www.mlcathome.org/mlds.html.

Each dataset archive contains a README.md file with details on what is included and some information on how to use it. Each trained network is in its own directory, with both the native PyTorch version of the saved model, a JSON file that contains the learned weights, and some metadata about each trained network, including a training history.

Currently available datasets are:

- MLDS-DS1: 100/ea, 500/ea, 1000/ea. (5000/ea and 10000/ea still computing)
- MLDS-DS2: 100/ea, 500/ea, 1000/ea. (5000/ea and 10000/ea still computing)
- MLDS-DS3: 100/ea (500/ea and 1000/ea zipping/uploading, 5000/ea and 10000/ea still computing)

The latter datasets are so large they would be better as torrents, so we may make them available only as torrents. For researchers, if you use these datasets, I ask that you a) let us know, and b) cite our paper when it comes available.

Detailed News
Lots of great work on a paper; stay tuned to the twitter account for some graphs and tables over the next week. Building the dataset archive takes a long time, because of the large number of files, and xz compression is not exactly fast. So DS3-500 and DS3-1000 might take a little while compress/upload.


Project status snapshot:
(note these numbers are approximations)






Last week's TWIM Notes: Feb 1 2021

Thanks again to all our volunteers!

-- The MLC@Home Admins(s)
Homepage: https://www.mlcathome.org/
Twitter: @MLCHome2

2021-02-08: SiDock@home, Fourth target (corona_RdRp_v1)

We are glad to announce the fourth target, corona_RdRp_v1. This molecule is frequently used in research studies as a potential target to inhibit viral replication. Specifically, it is SARS-CoV-2 RNA-dependent RNA polymerase (RdRp in short), an enzyme which coronavirus SARS-CoV-2 uses for the replication of its genome and the transcription of its genes.

2021-02-06: Kryptos@Home, Website and Project Maintenance at 02:00 PST / 05:00 EST / 10:00 UTC on Feb 7th

The project and website are going to be down on Feb 7th from 02:00 PST / 05:00 EST / 10:00 UTC for about 4 hours.
Apologies for any inconvenience this may cause.

2021-02-05: SiDock@home, Release CMDock v 0.1.1

Official release of CurieDock (CMDock v 0.1.1) for windows, linux and arm (raspberry pi):

https://gitlab.com/Jukic/cmdock/-/releases

2021-02-04: World Community Grid, January/February Update: OpenPandemics - COVID-19

Lab testing has begun for some of the promising compounds identified with the help of World Community Grid volunteers.

2021-02-04: SRBase, https config ongoing (done)

There was a short timeout of the server because Iam still testing the config but it will take some time. Have some help here. Got certbot and letsencrypt running with a successful message but the apache config is still messy. I hope I can find a way to setup this after years.

2021-02-04: SRBase, https config ongoing

There was a short timeout of the server because Iam still testing the config but it will take some time. Have some help here. Got certbot and letsencrypt running with a successful message but the apache config is still messy. I hope I can find a way to setup this after years.

2021-02-03: Van Der Waerden Numbers, VERSION 43000- IMPORTANT

Version 43000 has been uploaded to work around the issue of tasks not being validated (the code is also slight cleaner). Please reset the project (in simple view, project commands and reset project). Tasks with outdated version numbers may fail to validate.

2021-02-03: iThena, NMN magazine: "Internet security - reality or only illusion?" (Polish title: "Bezpiecze?stwo w sieci - rzeczywisto?? czy jedynie iluzja?")

An interview appeared in NMN magazine: "Internet security - reality or only illusion?" (Polish title: "Bezpiecze?stwo w sieci - rzeczywisto?? czy jedynie iluzja?").

Unfortunately, the content is only available in Polish.

However we strongly encourage you to read the content - you can find some words also about the iThena project.

Links:
NMN Magazine: https://www.nowoczesnamysl.pl/
PDF content: https://www.nowoczesnamysl.pl/?smd_process_download=1&download_id=882
PDF content (own mirror): https://doc.ithena.net/NMN-nr-4-5-grudzien-2020-styczen-2021.pdf

Twitter: https://twitter.com/iThenaProject/status/1357093256610394119

2021-02-03: MilkyWay@home, New Separation Runs 2/3/2021

Hey Everyone,

The following Separation runs had to come down due to the server outage:

de_modfit_80_bundle4_4s_south4s_bgset_4
de_modfit_81_bundle4_4s_south4s_bgset_4
de_modfit_82_bundle4_4s_south4s_bgset_4
de_modfit_83_bundle4_4s_south4s_bgset_4
de_modfit_86_bundle4_4s_south4s_bgset_4

I have put up the following new runs on the server:

de_modfit_80_bundle4_4s_south4s_bgset_7
de_modfit_81_bundle4_4s_south4s_bgset_7
de_modfit_82_bundle4_4s_south4s_bgset_7
de_modfit_83_bundle4_4s_south4s_bgset_7
de_modfit_84_bundle4_4s_south4s_bgset_7
de_modfit_85_bundle4_4s_south4s_bgset_7
de_modfit_86_bundle4_4s_south4s_bgset_7

The skip from 4 to 7 involves me putting test runs on the server while we were debugging some of the recent problems. Please let me know when stripes 84 and 85 begin throwing validation errors and I can take those down when the errors/runs ratio reaches ~10%.

Best,
Tom

2021-02-03: MilkyWay@home, The Last Couple Days

Hi Everyone,

As I'm sure you're all aware by now, the server went through a bit of maintenance the last couple days and now seems to be working normally. We had to clear out a lot of backlog workunits due to technical problems on our side. The bad news is that if you crunched workunits in the last two or three days, those workunits may have been deleted before they were validated, meaning that you might not be getting credit for them. The good news is that the server is working again and that we have taken precautions so that this won't happen again in the future.

Apologies for any inconvenience this may have caused. This caught us by surprise just as it caught all of you by surprise, and know that we will always try our best to communicate with you all when these sorts of things happen.

Best,
Tom

2021-02-02: MilkyWay@home, MilkyWay Maintainance Continuing 2/2/2021

Hi Everyone,

The MilkyWay@home server will continue to experience maintenance outages today as we work on resolving the problem with the transitioner. Again, thanks for all your patience. You can check the status of the server at any time at https://milkyway.cs.rpi.edu/milkyway/server_status.php.

Best,
Tom

2021-02-02: Van Der Waerden Numbers, Alpha Release!

We're officially releasing version 42000 to the public. The program has recreated our older bounds for primes up to 70 million, and all essential functions in the server have been stabilized. Happy crunching, everyone!

2021-02-02: MLC@Home, [TWIM Notes] Feb 1 2021 posted

MLC@Home has posted the Feb 1 2021 edition of its weekly "This Week In MLC@Home" newsletter!
Updates on dataset release, the paper, and we've now surpassed 1000 examples for each of D1/D2, meaning a greater mix of WUs in the future.

Read the update and join the discussion here.

2021-02-02: MLC@Home, [TWIM Notes] Feb 1 2021

This Week in MLC@Home
Notes for Feb 1 2021
A weekly summary of news and notes for MLC@Home

Summary
Paper coming together. The first round of datasets are cut and I will release them by the end of this week. Only issue is their size. I will likely make the full, larger datasets available as a torrent. Stay tuned for some new results and the big dataset release this week. The paper will follow shortly afterwards.

Detailed News
A few people have asked if they can help with the client itself. The MLDS app is open source, and available for perusal at https://gitlab.com/mlcathome/mlds . I've created a number of issues under https://gitlab.com/mlcathome/mlds/-/issues to show thigns that need to happen. Some of which could potentially be tackled by other developers. Only issue is their size. I will likely make the full, larger datasets available as a torrent. When released, please consider seeding if you can. We've made our goal of having over 1000 entries for DS1/DS2, which allows the dataset release. This means we'll start mixing in other types of WUs than just DS2 WUs into the GPU queue again, balancing between the remaining DS1/DS2 and DS3 WUs. When DS4 is ready, we'll rebalance again.


Project status snapshot:
(note these numbers are approximations)






Last week's TWIM Notes: Jan 26 2021

Thanks again to all our volunteers!

-- The MLC@Home Admins(s)
Homepage: https://www.mlcathome.org/
Twitter: @MLCHome2projuct-summary-

2021-02-01: MilkyWay@home, Milky Way Maintainance 2/1/2021

Hey Everyone,

The MilkyWay server will be going down from 4PM today until midnight. After this outage, we should have the server up and running as normal, and the workunit generation issue will hopefully be solved.

Best,
Tom

2021-02-01: Van Der Waerden Numbers, Server Failing to Send E-mails

The server has recently failed to send about 30 e-mails, most of them for team creation. Since we have recently reverted to a backup of our server, recently created accounts, teams, and new passwords may not exist. We'll try to get the server's e-mail feature to work as soon as possible. Sorry for any confusion.

2021-02-01: PrimeGrid, Another DIV Mega Prime!

On 27 January 2021, 17:13:11 UTC, PrimeGrid's Fermat Divisor Search found the Mega Prime:

25*2^8456828+1

The prime is 2,545,761 digits long and enters Chris Caldwell's ?The Largest Known Primes Database? ranked 74th overall.

The discovery was made by Wolfgang Schwieger (DeleteNull) of Germany using an AMD Ryzen 7 3700X 8-Core Processor with 16GB RAM, running Microsoft Windows 10 Professional x64 Edition. This computer took about 1 hour, 20 minutes to complete the primality test using LLR2. Wolfgang Schwieger is a member of the SETI.Germany team.

For more details, please see the official announcement.

2021-02-01: PrimeGrid, And Another DIV Mega Prime!

On 23 January 2021, 03:37:22 UTC, PrimeGrid's Fermat Divisor Search found the Mega Prime:

39*2^8413422+1

The prime is 2,532,694 digits long and enters Chris Caldwell's ?The Largest Known Primes Database? ranked 74th overall.

The discovery was made by Philipp Bliedung (pabliedung) using an Intel(R) Xeon(R) Gold 6140 CPU @ 2.30GHz with 1GB RAM, running Linux Ubuntu Ubuntu 18.04.3 LTS [4.15.0-72-generic|libc 2.27 (Ubuntu GLIBC 2.27-3ubuntu1.2)]. This computer took about 2 hours, 5 minutes to complete the primality test using LLR2. Philipp Bliedung is a member of the USA team.

For more details, please see the official announcement.

2021-02-01: PrimeGrid, 321 Mega Prime!

On 20 January 2021, 11:58:27 UTC, PrimeGrid's 321 Search found the Mega Prime:

3*2^16819291-1

The prime is 5,063,112 digits long and enters Chris Caldwell's ?The Largest Known Primes Database? ranked 21st overall.

The discovery was made by Rudi Tapper (ruditapper) of the United Kingdom using an AMD Ryzen Threadripper 3990X 64-Core Processor with 16GB RAM, running Microsoft Windows 10 Professional x64 Edition. This computer took about 5 hours, 40 minutes to complete the primality test using LLR2. Rudi Tapper is a member of the Antarctic Crunchers team.

For more details, please see the official announcement.

2021-02-01: PrimeGrid, Another DIV Mega Prime!

On 19 January 2021, 15:48:46 UTC, PrimeGrid's Fermat Divisor Search found the Mega Prime:

31*2^8348000+1

The prime is 2,513,000 digits long and enters Chris Caldwell's ?The Largest Known Primes Database? ranked 73rd overall.

The discovery was made by Igor Karpenko (A1ex01) of Ukraine using an Intel(R) Core(TM) i5-8400 CPU @ 2.80GHz with 4GB RAM, running Linux. This computer took about 2 hours, 52 minutes to complete the primality test using LLR. Igor Karpenko is a member of the Ukraine team.

For more details, please see the official announcement.

2021-02-01: PrimeGrid, Fermat Divisor Found!

On 14 January 2021, 18:15:44 UTC, PrimeGrid's Fermat Divisor Search found the Mega Prime:

27*2^7963247+1 Divides F(7963245)

The prime is 2,397,178 digits long and will enter Chris Caldwell's The Largest Known Primes Database ranked 74th overall. This is ranked 2nd for prime Fermat divisors, and it is also ranked 2nd for ?weighted? prime Fermat divisors.

The discovery was made by Tom Greer (tng) of the United States using an Intel(R) Xeon(R) Gold 6140 CPU @ 2.30GHz with 1GB RAM, running Linux Ubuntu. This computer took about 3 hours, 58 minutes to complete the primality test using LLR2. Tom Greer is a member of the Antarctic Crunchers team.

For more details, please see the official announcement.